An Analysis of Factors Affecting Medication Adherence and Disease Recurrence Rate in Asthma Patients
(1) Universitas Muhammadiyah Pekajangan Pekalongan
(2) Universitas Muhammadiyah Pekajangan Pekalongan
(3) Universitas Muhammadiyah Pekajangan Pekalongan
(4) Universitas Muhammadiyah Pekajangan Pekalongan
(*) Corresponding Author
Abstract
Medication adherence and disease recurrence rates in asthma patients greatly affect the patient's quality of life. Knowledge of factors that influence medication adherence and disease recurrence rates can significantly impact physical health and, consequently, patient quality of life. This study aims to identify factors that influence medication adherence and disease recurrence rates in patients with asthma. This study employed a descriptive analytical method with a multiple linear design. Data collection was conducted from July 5 to 30, 2025. Assessment of medication adherence was done by the Medication Adherence Report Scale (MARS) questionnaire and evaluation of disease recurrence rates using asthma recurrence questionnaires. The results of data analysis using multiple linear tests showed that factors influencing medication adherence in asthma patients were gender (29.35%), education (14.48%), and the triggers for relapse (21.34%). Factors that influence the rate of disease recurrence in asthma patients are education (17.5%), occupation (14.2%), and the triggers for relapse (76.1%). Based on the study's results, several factors similar to those influencing medication adherence and disease recurrence rates were identified, including education and the triggers for relapse.
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Ramey OL, Silva Almodóvar A, Nahata MC. Medication adherence in Medicare-enrolled older adults with asthma before and during the coronavirus disease 2019 pandemic. Annals of Allergy, Asthma and Immunology 2022;128:561-567.e1. https://doi.org/10.1016/j.anai.2022.02.010.
Rizal A. Pemaknaan Ritual Ajaran Kejawen pada Kelompok Paseduluran Di Perumahan Pejaya Anugrah Desa Kramat jegu Kecamatan Taman Kabupaten Sidoarjo. Universitas Wijaya Kusuma Surabaya 2018;6:1–7.
Dewi CIT, Wibawa A, Adhitya IPGS. Factors associated with asthma recurrence: a narative review. Kinesiology and Physiotherapy Comprehensive 2024;3:62–8. https://doi.org/10.62004/kpc.v3i3.51.
Herawati N, Nurhasanah S. Faktor Resiko yang Berhubungan dengan Kekambuhan Asma Bronkial Pada Pasien Asma Bronkial. Jurnal Pustaka Keperawatan (Pusat Akses Kajian Keperawatan) 2022;1:121–5. https://doi.org/10.55382/jurnalpustakakeperawatan.v1i2.359.
Permatasari D, Juwita DA, Putri HR, Desri NQ. The Effect of Medication Adherence and Asthma Control in Asthma Patients at a Public Health Center in Padang, Indonesia. Jurnal Sains Farmasi & Klinis 2023;9:190. https://doi.org/10.25077/jsfk.9.sup.190-195.2022.
Jansen EM, van de Hei SJ, Dierick BJH, Kerstjens HAM, Kocks JWH, van Boven JFM. Global burden of medication non-adherence in chronic obstructive pulmonary disease (COPD) and asthma: A narrative review of the clinical and economic case for smart inhalers. Journal of Thoracic Disease 2021;13:3846–64. https://doi.org/10.21037/jtd-20-2360.
Tabyshova A, Sooronbaev T, Akylbekov A, Mademilov M, Isakova A, Erkinbaeva A, et al. Medication availability and economic barriers to adherence in asthma and COPD patients in low-resource settings. Npj Primary Care Respiratory Medicine 2022;32. https://doi.org/10.1038/s41533-022-00281-z.
Neswita E, Laia M, Ardilla HY, Nurkholifah S, Ginting AS, Lubis AA, et al. the Effect of Drug Counseling on Patient Compliance At Adam Malik Central General Hospital Using the Pill Count Method. Jambura Journal of Health Sciences and Research 2023;5:342–8. https://doi.org/10.35971/jjhsr.v5i1.17428.
Alfian SD, Griselda M, Pratama MAA, Insani WN, Abdulah R, Wawruch M. Factors Influencing Medication Non-Adherence in Patients with Chronic Diseases and Disabilities: Insights from a National Survey in Indonesia. Patient Preference and Adherence 2025;19:1557–72. https://doi.org/10.2147/PPA.S508553.
Belachew EA, Netere AK, Sendekie AK. Medication regimen complexity and its impact on medication adherence and asthma control among patients with asthma in Ethiopian referral hospitals. Asthma Research and Practice 2022;8:1–11. https://doi.org/10.1186/s40733-022-00089-1.
Kemenkes RI. Survei Kesehatan Indonesia 2023 (SKI). Kemenkes 2023:235.
Qian Y, Cai C, Sun M, Lv D, Zhao Y. Analyses of Factors Associated with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Review. International Journal of COPD 2023;18:2707–23. https://doi.org/10.2147/COPD.S433183.
Alfian R, Putra MP. Uji Validitas Dan reliabilitas Kuesioner Medication Adherence Repost Scale (MARS) Terhadap Pasien Diabetes Mellitus. Jurnal Ilmiah Ibnu Sina 2017;2:176–83.
Kvarnström K, Westerholm A, Airaksinen M, Liira H. Factors contributing to medication adherence in patients with a chronic condition: A scoping review of qualitative research. Pharmaceutics 2021;13:1–41. https://doi.org/10.3390/pharmaceutics13071100.
Homętowska H, Świątoniowska-Lonc N, Klekowski J, Chabowski M, Jankowska-Polańska B. Treatment Adherence in Patients with Obstructive Pulmonary Diseases. International Journal of Environmental Research and Public Health 2022;19. https://doi.org/10.3390/ijerph191811573.
Dahlén E, Bergström A, Ödling M, Ekström S, Melén E, Kull I. Non-adherence and sub-optimal treatment with asthma medications in young adults: a population-based cohort study. Journal of Asthma 2022;59:1661–9. https://doi.org/10.1080/02770903.2021.1941092.
Chowdhury NU, Guntur VP, Newcomb DC, Wechsler ME. Sex and gender in asthma. European Respiratory Review 2021;30. https://doi.org/10.1183/16000617.0067-2021.
Kharaba Z, Feghali E, El Husseini F, Sacre H, Abou Selwan C, Saadeh S, et al. An Assessment of Quality of Life in Patients With Asthma Through Physical, Emotional, Social, and Occupational Aspects. A Cross-Sectional Study. Frontiers in Public Health 2022;10:1–8. https://doi.org/10.3389/fpubh.2022.883784.
Pan Z, Yang H, Jin Y, Zhou Q, Wang Q, Hao C, et al. Analysis of gender- and age-stratified asthma burden : forecasting prevalence trends in. Frontiers in Mecicine 2025:1–13. https://doi.org/10.3389/fmed.2025.1612688.
Toppila-Salmi S, Lemmetyinen R, Chanoine S, Karjalainen J, Pekkanen J, Bousquet J, et al. Risk factors for severe adult-onset asthma: a multi-factor approach. BMC Pulmonary Medicine 2021;21:1–11. https://doi.org/10.1186/s12890-021-01578-4.
Dandan JG, Frethernety A, Parhusip MBE. Literature Review : Gambaran Faktor-Faktor Pencetus Asma Pada Pasien Asma. Jurnal Kedokteran Universitas Palangka Raya 2022;10:1–5. https://doi.org/10.37304/jkupr.v10i2.3492.
Winugroho MLH, Kemuning AR, Rusmajati J, Desdiani. Prevalence And Clinical Characteristics Of Allergic Rhinitis Among Asthmatic Patients In The Emergency Departement Of Bhayangkara Brimob Hospital In Indonesia. Ibnu Sina : Jurnal Kedokteran Dan Kesehatan -Fakultas Kedokteran Universitas Islam Sumatera Utara 2025;24:460–7. https://doi.org/https://doi.org/10.30743/ibnusina.v24i2.930.
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DOI: https://doi.org/10.26714/mki.8.3.2025.179-186
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